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Other diseases of peritoneum

DOID EFO Endpoint Browser PheWeb

K11_OTHPERITON

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K66
  • Hospital discharge: ICD-9 — 568
  • Hospital discharge: ICD-8 — 569
  • Hospital discharge: excluded ICD-8 — 56902
  • Cause of death: ICD-10 — K66
  • Cause of death: ICD-9 — 568
  • Cause of death: ICD-8 — 569
  • Cause of death: excluded ICD-8 — 56902

2 out of 7 registries used, show all original rules.

1563

4. Check minimum number of events

None

1563

5. Include endpoints

None

1563

6. Filter based on genotype QC (FinnGen only)

1500

Control definitions (FinnGen only)

Control exclude K11_PERITON

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K65-K67
Name in latin Aliae morbositates peritonei

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 15019 9767 5049
Only index persons 11222 7846 3376
Unadjusted period prevalence (%)
Whole population 0.23 0.28 0.14
Only index persons 0.24 0.29 0.13
Median age at first event (years)
Whole population 47.02 47.13 46.44
Only index persons 41.64 43.17 38.08

-FinnGen-

Key figures

All Female Male
Number of individuals 1500 1059 441
Unadjusted period prevalence (%) 0.36 0.42 0.22
Median age at first event (years) 42.64 41.82 44.61

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Association

Association between endpoint K11_OTHPERITON and mortality.

Females

Parameter HR [95% CI] p-value
K11_OTHPERITON 1.474 [1.29, 1.68] < 0.001
Birth year 0.994 [0.99, 1.0] 0.169

During the follow-up period (1.1.1998 — 31.12.2019), 542 out of 3633 females with K11_OTHPERITON died.

Males

Parameter HR [95% CI] p-value
K11_OTHPERITON 1.577 [1.33, 1.87] < 0.001
Birth year 0.988 [0.98, 1.0] 0.026

During the follow-up period (1.1.1998 — 31.12.2019), 305 out of 1141 males with K11_OTHPERITON died.

Mortality risk

Mortality risk for people of age

years, who have K11_OTHPERITON.

N-year risk Females Males
1 0.072% 0.306%
5 0.756% 1.774%
10 1.976% 4.635%
15 3.855% 8.783%
20 6.688% 14.661%

Relationships between endpoints

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Index endpoint: K11_OTHPERITON – Other diseases of peritoneum

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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