No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
3216 |
4. Check minimum number of eventsNone |
3216 |
5. Include endpointsNone |
3216 |
6. Filter based on genotype QC (FinnGen only) |
3010 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF6
Similar endpoints
↥List of similar endpoints to
Chronic periodontitis, complicated
based on the number of shared cases.
Similar with more cases:
- Chronic periodontitis
- Chronic periodontitis , including avohilmo
- Parodontitis
- Parodontitis or operation codes
- Gingivitis and periodontal diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 19988 | 8250 | 11538 |
| Only index persons | 18817 | 7946 | 10871 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.29 | 0.24 | 0.32 |
| Only index persons | 0.36 | 0.29 | 0.41 |
| Median age at first event (years) | |||
| Whole population | 60.66 | 60.71 | 60.85 |
| Only index persons | 60.69 | 60.61 | 60.76 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3010 | 1248 | 1762 |
| Unadjusted period prevalence (%) | 0.72 | 0.49 | 0.88 |
| Median age at first event (years) | 61.70 | 59.96 | 62.94 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_PERIODON_CHRON_COMPL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PERIODON_CHRON_COMPL | 3.04 [2.64, 3.51] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.502 |
During the follow-up period (1.1.1998 — 31.12.2019), 1517 out of 6616 females with K11_PERIODON_CHRON_COMPL died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PERIODON_CHRON_COMPL | 3.497 [3.06, 3.99] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 2926 out of 9261 males with K11_PERIODON_CHRON_COMPL died.
Mortality risk
Mortality risk for people of age
years, who have K11_PERIODON_CHRON_COMPL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.374% | 0.508% |
| 5 | 1.811% | 3.643% |
| 10 | 4.625% | 9.287% |
| 15 | 8.65% | 17.216% |
| 20 | 15.042% | 27.72% |
Relationships between endpoints
↥Index endpoint: K11_PERIODON_CHRON_COMPL – Chronic periodontitis, complicated
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data