No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
124055 |
4. Check minimum number of eventsNone |
124055 |
5. Include endpointsNone |
124055 |
6. Filter based on genotype QC (FinnGen only) |
118404 |
Control definitions (FinnGen only)
Extra metadata
Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 1126339 | 605054 | 512819 |
Only index persons | 1095088 | 594583 | 500505 |
Unadjusted period prevalence (%) | |||
Whole population | 15.90 | 17.33 | 14.33 |
Only index persons | 20.60 | 21.86 | 19.11 |
Median age at first event (years) | |||
Whole population | 41.64 | 41.70 | 41.70 |
Only index persons | 42.17 | 42.15 | 42.20 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 118404 | 73319 | 45085 |
Unadjusted period prevalence (%) | 26.45 | 28.80 | 22.64 |
Median age at first event (years) | 53.80 | 50.84 | 58.62 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_GINGIVITIS_PERIODONTAL and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
K11_GINGIVITIS_PERIODONTAL | 1.243 [1.04, 1.49] | 0.018 |
Birth year | 0.992 [0.98, 1.0] | 0.047 |
During the follow-up period (1.1.1998 — 31.12.2019), 15525 out of 477374 females with K11_GINGIVITIS_PERIODONTAL died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
K11_GINGIVITIS_PERIODONTAL | 1.331 [1.13, 1.57] | < 0.001 |
Birth year | 0.985 [0.98, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 20783 out of 397801 males with K11_GINGIVITIS_PERIODONTAL died.
Mortality risk
Mortality risk for people of age
years, who have K11_GINGIVITIS_PERIODONTAL.N-year risk | Females | Males |
---|---|---|
1 | 0.099% | 0.2% |
5 | 0.564% | 1.247% |
10 | 1.527% | 3.201% |
15 | 2.858% | 6.3% |
20 | 5.14% | 10.533% |
Relationships between endpoints
↥Index endpoint: K11_GINGIVITIS_PERIODONTAL – Gingivitis and periodontal diseases
GWS hits: 2