≡ Risteys
FG R11 + FR

Documentation Changelog GitHub Contact & Feedback

Other and unspecified abdominal hernia

DOID EFO Endpoint Browser PheWeb

K11_OTHABDHER

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K45, K46
  • Hospital discharge: ICD-9 — 551[8-9]|552[8-9]|553[8-9]
  • Hospital discharge: ICD-8 — 551[8-9]
  • Cause of death: ICD-10 — K45, K46
  • Cause of death: ICD-9 — 551[8-9]|552[8-9]|553[8-9]
  • Cause of death: ICD-8 — 551[8-9]

2 out of 7 registries used, show all original rules.

1349

4. Check minimum number of events

None

1349

5. Include endpoints

None

1349

6. Filter based on genotype QC (FinnGen only)

1307

Control definitions (FinnGen only)

Control exclude K11_HERNIA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11376 6164 5110
Only index persons 9484 5301 4183
Unadjusted period prevalence (%)
Whole population 0.16 0.18 0.14
Only index persons 0.18 0.19 0.16
Median age at first event (years)
Whole population 59.82 61.30 57.99
Only index persons 57.88 59.29 56.11

-FinnGen-

Key figures

All Female Male
Number of individuals 1307 722 585
Unadjusted period prevalence (%) 0.29 0.28 0.29
Median age at first event (years) 59.15 57.20 61.55

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

↥

Association

Association between endpoint K11_OTHABDHER and mortality.

Females

Parameter HR [95% CI] p-value
K11_OTHABDHER 1.483 [1.31, 1.68] < 0.001
Birth year 0.992 [0.98, 1.0] 0.067

During the follow-up period (1.1.1998 — 31.12.2019), 986 out of 3918 females with K11_OTHABDHER died.

Males

Parameter HR [95% CI] p-value
K11_OTHABDHER 1.544 [1.35, 1.77] < 0.001
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 858 out of 3018 males with K11_OTHABDHER died.

Mortality risk

Mortality risk for people of age

years, who have K11_OTHABDHER.

N-year risk Females Males
1 0.122% 0.25%
5 0.813% 1.527%
10 2.132% 3.895%
15 3.966% 7.384%
20 6.631% 12.183%

Relationships between endpoints

↥

Index endpoint: K11_OTHABDHER – Other and unspecified abdominal hernia

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data