No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditions
|
1201 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
903 |
4. Check minimum number of eventsNone |
903 |
5. Include endpointsNone |
903 |
6. Filter based on genotype QC (FinnGen only) |
868 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF7
Similar endpoints
↥List of similar endpoints to
Mandibular retrognathia AND surgery (BSSRO)
based on the number of shared cases.
Similar with more cases:
- Bilateral sagittal split ramus osteotomy operation
- LeFortI or BSSRO operation
- Mandibular retrognathia
- Dentofacial anomalies [including malocclusion]
- Diseases of oral cavity, salivary glands and jaws
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6120 | 4159 | 1944 |
| Only index persons | 6048 | 4126 | 1922 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.12 | 0.05 |
| Only index persons | 0.13 | 0.15 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 35.50 | 35.14 | 36.32 |
| Only index persons | 35.57 | 35.18 | 36.41 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 868 | 640 | 228 |
| Unadjusted period prevalence (%) | 0.22 | 0.25 | 0.11 |
| Median age at first event (years) | 38.01 | 36.98 | 40.91 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_MN_RETRGN_AND_SURG and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have K11_MN_RETRGN_AND_SURG.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: K11_MN_RETRGN_AND_SURG – Mandibular retrognathia AND surgery (BSSRO)
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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