No definition available.
Missing teeth due to accident, extraction or parodontitis
K11_MISS_TEETH_ACCID_EXTR_PAROD
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
4287 |
4. Check minimum number of eventsNone |
4287 |
5. Include endpointsNone |
4287 |
6. Filter based on genotype QC (FinnGen only) |
4112 |
Control definitions (FinnGen only)
Control exclude
K11_ORAL
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6
Similar endpoints
↥List of similar endpoints to
Missing teeth due to accident, extraction or parodontitis
based on the number of shared cases.
Similar with more cases:
- Other disorders of teeth and supporting structures
- Diseases of oral cavity, salivary glands and jaws
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 25891 | 13411 | 12357 |
| Only index persons | 24807 | 13019 | 11788 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.36 | 0.38 | 0.35 |
| Only index persons | 0.47 | 0.48 | 0.45 |
| Median age at first event (years) | |||
| Whole population | 59.85 | 59.96 | 59.85 |
| Only index persons | 59.80 | 59.88 | 59.71 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 4112 | 2229 | 1883 |
| Unadjusted period prevalence (%) | 0.91 | 0.88 | 0.95 |
| Median age at first event (years) | 61.25 | 59.67 | 63.13 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_MISS_TEETH_ACCID_EXTR_PAROD and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_MISS_TEETH_ACCID_EXTR_PAROD | 1.903 [1.69, 2.15] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.036 |
During the follow-up period (1.1.1998 — 31.12.2019), 1770 out of 11167 females with K11_MISS_TEETH_ACCID_EXTR_PAROD died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_MISS_TEETH_ACCID_EXTR_PAROD | 2.118 [1.86, 2.41] | < 0.001 |
| Birth year | 0.986 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 2337 out of 10070 males with K11_MISS_TEETH_ACCID_EXTR_PAROD died.
Mortality risk
Mortality risk for people of age
years, who have K11_MISS_TEETH_ACCID_EXTR_PAROD.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.127% | 0.381% |
| 5 | 0.894% | 2.409% |
| 10 | 2.377% | 5.934% |
| 15 | 4.567% | 11.709% |
| 20 | 7.775% | 19.073% |
Relationships between endpoints
↥Index endpoint: K11_MISS_TEETH_ACCID_EXTR_PAROD – Missing teeth due to accident, extraction or parodontitis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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