Molar incisor enamel hypoplasia, with caries

K11_MIH_CARIES

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

  • K11_CARIES
11473

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

3 out of 7 registries used, show all original rules.

232

4. Check minimum number of events

None

232

5. Include endpoints

232

6. Filter based on genotype QC (FinnGen only)

208

Control definitions (FinnGen only)

Control conditions not K11_CARIES

Extra metadata

First used in FinnGen datafreeze DF10

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2382 1118 1261
Only index persons 1584 754 830
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.04
Only index persons 0.03 0.03 0.03
Median age at first event (years)
Whole population 8.86 8.93 8.74
Only index persons 11.23 11.43 11.04

-FinnGen-

Key figures

All Female Male
Number of individuals 208 107 101
Unadjusted period prevalence (%) 0.05 0.04 0.05
Median age at first event (years) 8.24 8.84 7.61

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

Association

Association between endpoint K11_MIH_CARIES and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_MIH_CARIES.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: K11_MIH_CARIES – Molar incisor enamel hypoplasia, with caries

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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