No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
910 |
4. Check minimum number of eventsNone |
910 |
5. Include endpoints |
910 |
6. Filter based on genotype QC (FinnGen only) |
852 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF10
Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 26829 | 14582 | 12214 |
Only index persons | 19103 | 10748 | 8355 |
Unadjusted period prevalence (%) | |||
Whole population | 0.38 | 0.42 | 0.34 |
Only index persons | 0.36 | 0.40 | 0.32 |
Median age at first event (years) | |||
Whole population | 10.94 | 11.50 | 10.22 |
Only index persons | 13.36 | 13.99 | 12.56 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 852 | 574 | 278 |
Unadjusted period prevalence (%) | 0.20 | 0.23 | 0.14 |
Median age at first event (years) | 17.41 | 20.05 | 11.96 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_MIH and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have K11_MIH.N-year risk | Females | Males |
---|---|---|
1 | No data | No data |
5 | No data | No data |
10 | No data | No data |
15 | No data | No data |
20 | No data | No data |
Relationships between endpoints
↥Index endpoint: K11_MIH – Molar incisor enamel hypoplasia
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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