Hypoplasia of dental enamel, prenatal

K11_HYPOPLASIA_ENAMEL_PRENATAL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K00.41
  • Cause of death: ICD-10 K00.41

2 out of 7 registries used, show all original rules.

57

4. Check minimum number of events

None

57

5. Include endpoints

None

57

6. Filter based on genotype QC (FinnGen only)

52

Control definitions (FinnGen only)

Control exclude K11_MIH

Extra metadata

First used in FinnGen datafreeze DF10

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 444 197 247
Only index persons 110 54 56
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population - 4.63 4.01
Only index persons 8.81 9.75 7.90

-FinnGen-

Key figures

All Female Male
Number of individuals 52 21 31
Unadjusted period prevalence (%) 0.01 0.01 0.02
Median age at first event (years) 4.19 5.00 3.64

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

Association

Association between endpoint K11_HYPOPLASIA_ENAMEL_PRENATAL and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_HYPOPLASIA_ENAMEL_PRENATAL.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: K11_HYPOPLASIA_ENAMEL_PRENATAL – Hypoplasia of dental enamel, prenatal

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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