No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
704 |
4. Check minimum number of eventsNone |
704 |
5. Include endpointsNone |
704 |
6. Filter based on genotype QC (FinnGen only) |
687 |
Control definitions (FinnGen only)
Control exclude
K11_INTESTOTH
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K56
Name in latin
Invaginatio intestini
Similar endpoints
↥List of similar endpoints to
Intussusception
based on the number of shared cases.
Similar with more cases:
- Paralytic ileus and intestinal obstruction
- Other diseases of intestines
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5617 | 3736 | 1861 |
| Only index persons | 4964 | 3463 | 1501 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.11 | 0.05 |
| Only index persons | 0.11 | 0.13 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 50.22 | 60.81 | 28.73 |
| Only index persons | 50.58 | 60.78 | 27.05 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 687 | 535 | 152 |
| Unadjusted period prevalence (%) | 0.18 | 0.21 | 0.08 |
| Median age at first event (years) | 57.08 | 58.39 | 52.45 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint K11_INTUSS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_INTUSS | 1.281 [1.07, 1.53] | 0.006 |
| Birth year | 0.996 [0.99, 1.0] | 0.363 |
During the follow-up period (1.1.1998 — 31.12.2019), 334 out of 2809 females with K11_INTUSS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_INTUSS | 2.788 [1.96, 3.96] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 265 out of 1029 males with K11_INTUSS died.
Mortality risk
Mortality risk for people of age
years, who have K11_INTUSS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.137% | 0.581% |
| 5 | 0.777% | 3.046% |
| 10 | 1.956% | 7.562% |
| 15 | 3.914% | 14.165% |
| 20 | 7.014% | 23.381% |
Relationships between endpoints
↥Index endpoint: K11_INTUSS – Intussusception
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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