No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1129 |
4. Check minimum number of eventsNone |
1129 |
5. Include endpoints |
1737 |
6. Filter based on genotype QC (FinnGen only) |
1659 |
Control definitions (FinnGen only)
Control exclude
K11_ORAL
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Other disorders of gingiva or/and edentulous alveolar ridge
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 13283 | 7429 | 5800 |
| Only index persons | 12308 | 6983 | 5325 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.19 | 0.21 | 0.16 |
| Only index persons | 0.23 | 0.26 | 0.20 |
| Median age at first event (years) | |||
| Whole population | 52.89 | 53.09 | 52.73 |
| Only index persons | 52.86 | 52.99 | 52.69 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1659 | 924 | 735 |
| Unadjusted period prevalence (%) | 0.37 | 0.36 | 0.37 |
| Median age at first event (years) | 56.47 | 53.48 | 60.23 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_GINGIVA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_GINGIVA | 1.525 [1.35, 1.72] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.259 |
During the follow-up period (1.1.1998 — 31.12.2019), 974 out of 6249 females with K11_GINGIVA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_GINGIVA | 1.822 [1.59, 2.09] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 934 out of 4898 males with K11_GINGIVA died.
Mortality risk
Mortality risk for people of age
years, who have K11_GINGIVA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.169% | 0.308% |
| 5 | 0.806% | 1.93% |
| 10 | 2.317% | 5.249% |
| 15 | 4.34% | 9.737% |
| 20 | 7.696% | 15.974% |
Relationships between endpoints
↥Index endpoint: K11_GINGIVA – Other disorders of gingiva or/and edentulous alveolar ridge
GWS hits: 4
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data