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Fissure and fistula of anal and rectal regions

K11_FISSANAL

anus disease: A non-neoplastic or neoplastic disorder that affects the anal canal or anal margin. Representative examples of non-neoplastic disorders include hemorrhoids and anal ulcer. Representative examples of neoplastic disorders include carcinoma, lymphoma, and melanoma. [database_cross_reference: NCIT:C26695]

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K60
  • Hospital discharge: ICD-9 565
  • Hospital discharge: ICD-8 565
  • Cause of death: ICD-10 K60
  • Cause of death: ICD-9 565
  • Cause of death: ICD-8 565

2 out of 7 registries used, show all original rules.

10670

4. Check minimum number of events

None

10670

5. Include endpoints

None

10670

6. Filter based on genotype QC (FinnGen only)

10270

Control definitions (FinnGen only)

Control exclude K11_INTESTOTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K55-K63
Name in latin Fissura/fistula regionis analis/rectalis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 10270 5377 4893
Unadjusted period prevalence (%) 2.28 2.11 2.46
Median age at first event (years) 44.33 43.02 45.76

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: K11_FISSANAL – Fissure and fistula of anal and rectal regions

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).