viral pneumonia: Inflammation of the lung parenchyma that is caused by a viral infection.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
4710 |
4. Check minimum number of eventsNone |
4710 |
5. Include endpointsNone |
4710 |
6. Filter based on genotype QC (FinnGen only) |
4466 |
Control definitions (FinnGen only)
Control exclude
J10_INFLUPNEU
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Viral pneumonia
based on the number of shared cases.
Similar with more cases:
- All pneumoniae
- Influenza and pneumonia
- Diseases of the respiratory system
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 47722 | 21518 | 25878 |
| Only index persons | 39771 | 17942 | 21829 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.67 | 0.62 | 0.72 |
| Only index persons | 0.75 | 0.66 | 0.83 |
| Median age at first event (years) | |||
| Whole population | 49.11 | 56.07 | 43.15 |
| Only index persons | 46.32 | 54.15 | 39.88 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 4466 | 2112 | 2354 |
| Unadjusted period prevalence (%) | 1.02 | 0.83 | 1.18 |
| Median age at first event (years) | 58.44 | 55.30 | 61.26 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint J10_VIRALPNEUMO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_VIRALPNEUMO | 2.106 [1.81, 2.45] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.374 |
During the follow-up period (1.1.1998 — 31.12.2019), 3232 out of 13001 females with J10_VIRALPNEUMO died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_VIRALPNEUMO | 2.569 [2.15, 3.07] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.026 |
During the follow-up period (1.1.1998 — 31.12.2019), 3434 out of 14173 males with J10_VIRALPNEUMO died.
Mortality risk
Mortality risk for people of age
years, who have J10_VIRALPNEUMO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.231% | 0.533% |
| 5 | 1.239% | 3.194% |
| 10 | 3.122% | 8.332% |
| 15 | 6.231% | 15.11% |
| 20 | 10.83% | 24.933% |
Relationships between endpoints
↥Index endpoint: J10_VIRALPNEUMO – Viral pneumonia
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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