No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
17348 |
4. Check minimum number of eventsNone |
17348 |
5. Include endpointsNone |
17348 |
6. Filter based on genotype QC (FinnGen only) |
16717 |
Control definitions (FinnGen only)
Control exclude
J10_UPPERINFEC
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
J00-J06
Name in latin
Tonsillitis (palatina) acuta
Similar endpoints
↥List of similar endpoints to
Other and unspecified tonsillitis
based on the number of shared cases.
Similar with more cases:
- Acute upper respiratory infections
- Asthma/COPD-related acute respiratory infections
- COPD/asthma/ILD related infections
- COPD/asthma related infections
- Diseases of the respiratory system
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 230245 | 84623 | 144924 |
| Only index persons | 209544 | 76863 | 132681 |
| Unadjusted period prevalence (%) | |||
| Whole population | 3.44 | 2.42 | 4.05 |
| Only index persons | 4.24 | 2.83 | 5.06 |
| Median age at first event (years) | |||
| Whole population | 19.30 | 18.34 | 19.81 |
| Only index persons | 19.59 | 19.06 | 19.90 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 16717 | 7707 | 9010 |
| Unadjusted period prevalence (%) | 3.83 | 3.03 | 4.53 |
| Median age at first event (years) | 21.41 | 22.81 | 20.21 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint J10_TONSILLITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_TONSILLITIS | 1.456 [1.21, 1.75] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.143 |
During the follow-up period (1.1.1998 — 31.12.2019), 1140 out of 67683 females with J10_TONSILLITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_TONSILLITIS | 1.265 [1.09, 1.47] | 0.002 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 1588 out of 69183 males with J10_TONSILLITIS died.
Mortality risk
Mortality risk for people of age
years, who have J10_TONSILLITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.087% | 0.28% |
| 5 | 0.704% | 1.434% |
| 10 | 1.997% | 3.621% |
| 15 | 3.82% | 6.825% |
| 20 | 6.791% | 11.862% |
Relationships between endpoints
↥Index endpoint: J10_TONSILLITIS – Other and unspecified tonsillitis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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