sinusitis: An acute or chronic inflammatory process affecting the mucous membranes of any sinus cavity.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
26472 |
4. Check minimum number of eventsNone |
26472 |
5. Include endpointsNone |
26472 |
6. Filter based on genotype QC (FinnGen only) |
25620 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Acute sinusitis based on the number of shared cases.
Similar with more cases:
- Acute upper respiratory infections
- Asthma/COPD-related acute respiratory infections
- COPD/asthma/ILD related infections
- COPD/asthma related infections
- Diseases of the respiratory system
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 246100 | 116994 | 127821 |
Only index persons | 222657 | 106627 | 116030 |
Unadjusted period prevalence (%) | |||
Whole population | 3.45 | 3.35 | 3.57 |
Only index persons | 4.19 | 3.92 | 4.43 |
Median age at first event (years) | |||
Whole population | 28.88 | 37.98 | 20.35 |
Only index persons | 27.83 | 36.15 | 20.18 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 25620 | 15131 | 10489 |
Unadjusted period prevalence (%) | 5.67 | 5.94 | 5.27 |
Median age at first event (years) | 33.76 | 38.63 | 26.74 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint J10_SINUSITIS and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
J10_SINUSITIS | 1.39 [1.28, 1.51] | < 0.001 |
Birth year | 0.997 [0.99, 1.01] | 0.509 |
During the follow-up period (1.1.1998 — 31.12.2019), 8951 out of 80536 females with J10_SINUSITIS died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
J10_SINUSITIS | 1.609 [1.47, 1.76] | < 0.001 |
Birth year | 0.986 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 8197 out of 62147 males with J10_SINUSITIS died.
Mortality risk
Mortality risk for people of age
years, who have J10_SINUSITIS.N-year risk | Females | Males |
---|---|---|
1 | 0.174% | 0.373% |
5 | 0.875% | 1.645% |
10 | 2.12% | 4.408% |
15 | 3.965% | 8.101% |
20 | 7.36% | 13.499% |
Relationships between endpoints
↥Index endpoint: J10_SINUSITIS – Acute sinusitis
GWS hits: 7