No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
6407 |
4. Check minimum number of eventsNone |
6407 |
5. Include endpointsNone |
6407 |
6. Filter based on genotype QC (FinnGen only) |
6139 |
Control definitions (FinnGen only)
Control exclude
J10_UPPERINFEC
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
J00-J06
Name in latin
Pharyngitis acuta
Similar endpoints
↥List of similar endpoints to
Acute pharyngitis
based on the number of shared cases.
Similar with more cases:
- Acute upper respiratory infections
- Asthma/COPD-related acute respiratory infections
- COPD/asthma/ILD related infections
- COPD/asthma related infections
- Diseases of the respiratory system
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 90684 | 39064 | 51242 |
| Only index persons | 76024 | 32838 | 43186 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.29 | 1.12 | 1.43 |
| Only index persons | 1.46 | 1.21 | 1.65 |
| Median age at first event (years) | |||
| Whole population | 19.66 | 19.37 | 19.79 |
| Only index persons | 20.72 | 21.59 | 20.06 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 6139 | 3168 | 2971 |
| Unadjusted period prevalence (%) | 1.36 | 1.24 | 1.49 |
| Median age at first event (years) | 25.91 | 30.83 | 20.66 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint J10_PHARYNGITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_PHARYNGITIS | 1.471 [1.17, 1.85] | 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.05 |
During the follow-up period (1.1.1998 — 31.12.2019), 685 out of 30593 females with J10_PHARYNGITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_PHARYNGITIS | 1.637 [1.37, 1.96] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 960 out of 28863 males with J10_PHARYNGITIS died.
Mortality risk
Mortality risk for people of age
years, who have J10_PHARYNGITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.118% | 0.286% |
| 5 | 0.787% | 1.944% |
| 10 | 2.019% | 4.799% |
| 15 | 3.724% | 8.91% |
| 20 | 6.323% | 14.94% |
Relationships between endpoints
↥Index endpoint: J10_PHARYNGITIS – Acute pharyngitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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