No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
863 |
4. Check minimum number of eventsNone |
863 |
5. Include endpointsNone |
863 |
6. Filter based on genotype QC (FinnGen only) |
833 |
Control definitions (FinnGen only)
Control exclude
K11_HERNIA
Extra metadata
First used in FinnGen datafreeze
DF3
Similar endpoints
↥List of similar endpoints to
Inguinal hernia, unilateral
based on the number of shared cases.
Similar with more cases:
- Femoral hernia, unilateral
- Inguinal of femoral hernia, unilateral
- Femoral hernia
- Hernia
- Gastrointestinal diseases
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8437 | 5168 | 3231 |
| Only index persons | 7546 | 4656 | 2890 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.13 | 0.15 | 0.09 |
| Only index persons | 0.15 | 0.17 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 64.81 | 66.55 | 61.92 |
| Only index persons | 62.89 | 64.41 | 60.44 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 833 | 475 | 358 |
| Unadjusted period prevalence (%) | 0.18 | 0.19 | 0.18 |
| Median age at first event (years) | 60.11 | 58.54 | 62.19 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint HERING_UNILATERAL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| HERING_UNILATERAL | 1.295 [1.16, 1.44] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.062 |
During the follow-up period (1.1.1998 — 31.12.2019), 1286 out of 4333 females with HERING_UNILATERAL died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| HERING_UNILATERAL | 1.073 [0.95, 1.21] | 0.246 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 809 out of 2808 males with HERING_UNILATERAL died.
Mortality risk
Mortality risk for people of age
years, who have HERING_UNILATERAL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.119% | 0.186% |
| 5 | 0.747% | 1.151% |
| 10 | 1.797% | 3.065% |
| 15 | 3.311% | 5.71% |
| 20 | 5.777% | 9.605% |
Relationships between endpoints
↥Index endpoint: HERING_UNILATERAL – Inguinal hernia, unilateral
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data