suppurative otitis media: Inflammation of the middle ear with purulent discharge.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
912 |
4. Check minimum number of eventsNone |
912 |
5. Include endpointsNone |
912 |
6. Filter based on genotype QC (FinnGen only) |
867 |
Control definitions (FinnGen only)
Control exclude
H8_MIDDLEMASTOID
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H66
Name in latin
Otitis media purulenta chronica non specificata
Similar endpoints
↥List of similar endpoints to
Suppurative otitis media, unspecified
based on the number of shared cases.
Similar with more cases:
- Suppurative and unspecified otitis media
- Diseases of middle ear and mastoid
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 14084 | 6111 | 7921 |
| Only index persons | 11984 | 5233 | 6751 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.20 | 0.18 | 0.22 |
| Only index persons | 0.23 | 0.19 | 0.26 |
| Median age at first event (years) | |||
| Whole population | 5.39 | 6.82 | 3.92 |
| Only index persons | 6.48 | 9.38 | 4.23 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 867 | 471 | 396 |
| Unadjusted period prevalence (%) | 0.19 | 0.18 | 0.20 |
| Median age at first event (years) | 34.82 | 26.40 | 44.84 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H8_SUP_OTINAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_SUP_OTINAS | 1.229 [1.1, 1.37] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.263 |
During the follow-up period (1.1.1998 — 31.12.2019), 641 out of 3842 females with H8_SUP_OTINAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_SUP_OTINAS | 1.206 [1.08, 1.35] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 752 out of 4438 males with H8_SUP_OTINAS died.
Mortality risk
Mortality risk for people of age
years, who have H8_SUP_OTINAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.15% | 0.237% |
| 5 | 0.584% | 1.523% |
| 10 | 1.543% | 3.554% |
| 15 | 3.269% | 6.65% |
| 20 | 5.801% | 11.043% |
Relationships between endpoints
↥Index endpoint: H8_SUP_OTINAS – Suppurative otitis media, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data