≡ Risteys
FG R11 + FR

Documentation Changelog GitHub Contact & Feedback

Otitis externa, unspecified

DOID EFO Endpoint Browser PheWeb

H8_EXT_NAS

otitis externa: Inflammation of the anatomical structures of the outer ear and ear canal secondary to an infectious process. Bacterial etiology is most common, but fungal infection is also possible. Symptoms include erythema, edema, and pain.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H60.9
  • Hospital discharge: ICD-9 — 3801A|3801B
  • Hospital discharge: ICD-8 — 3800[2-9]
  • Cause of death: ICD-10 — H60.9
  • Cause of death: ICD-9 — 3801A|3801B
  • Cause of death: ICD-8 — 3800[2-9]

2 out of 7 registries used, show all original rules.

4015

4. Check minimum number of events

None

4015

5. Include endpoints

None

4015

6. Filter based on genotype QC (FinnGen only)

3850

Control definitions (FinnGen only)

Control exclude H8_EXTERNAL

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H60
Name in latin Otitis externa non specificata

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 38404 19660 18498
Only index persons 34180 17838 16342
Unadjusted period prevalence (%)
Whole population 0.54 0.56 0.52
Only index persons 0.64 0.66 0.62
Median age at first event (years)
Whole population 36.52 36.72 36.29
Only index persons 38.41 38.38 38.46

-FinnGen-

Key figures

All Female Male
Number of individuals 3850 2275 1575
Unadjusted period prevalence (%) 0.85 0.89 0.79
Median age at first event (years) 48.94 45.21 54.33

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

↥

Association

Association between endpoint H8_EXT_NAS and mortality.

Females

Parameter HR [95% CI] p-value
H8_EXT_NAS 1.425 [1.19, 1.7] < 0.001
Birth year 0.994 [0.99, 1.0] 0.165

During the follow-up period (1.1.1998 — 31.12.2019), 864 out of 13978 females with H8_EXT_NAS died.

Males

Parameter HR [95% CI] p-value
H8_EXT_NAS 1.398 [1.17, 1.67] < 0.001
Birth year 0.982 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 1080 out of 12644 males with H8_EXT_NAS died.

Mortality risk

Mortality risk for people of age

years, who have H8_EXT_NAS.

N-year risk Females Males
1 0.155% 0.237%
5 0.938% 1.258%
10 2.119% 3.158%
15 4.09% 6.345%
20 6.855% 11.082%

Relationships between endpoints

↥

Index endpoint: H8_EXT_NAS – Otitis externa, unspecified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data