No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
55 |
4. Check minimum number of eventsNone |
55 |
5. Include endpointsNone |
55 |
6. Filter based on genotype QC (FinnGen only) |
50 |
Control definitions (FinnGen only)
Control exclude
H8_EXTERNAL
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H60
Name in latin
Otitis externa [maligna]
Similar endpoints
↥List of similar endpoints to
Malignant otitis externa
based on the number of shared cases.
Similar with more cases:
- Otitis externa
- Diseases of external ear
- Diseases of the ear and mastoid process
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 540 | 251 | 283 |
| Only index persons | 480 | 228 | 252 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 54.45 | 50.70 | 57.43 |
| Only index persons | 53.03 | 48.66 | 56.98 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 50 | 25 | 25 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 54.22 | 48.02 | 60.42 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H8_EXT_MALIGN and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXT_MALIGN | 1.384 [0.95, 2.01] | 0.086 |
| Birth year | 0.989 [0.98, 1.0] | 0.022 |
During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 238 males with H8_EXT_MALIGN died.
Mortality risk
Mortality risk for people of age
years, who have H8_EXT_MALIGN.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.279% |
| 5 | No data | 1.591% |
| 10 | No data | 4.158% |
| 15 | No data | 8.048% |
| 20 | No data | 13.472% |
Relationships between endpoints
↥Index endpoint: H8_EXT_MALIGN – Malignant otitis externa
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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