eyelid disease: A disease involving the eyelid.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
288 |
4. Check minimum number of eventsNone |
288 |
5. Include endpointsNone |
288 |
6. Filter based on genotype QC (FinnGen only) |
277 |
Control definitions (FinnGen only)
Control exclude
H7_LIDLACRIMALORBIT
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H02
Name in latin
Xanthelasma palpebrae
Similar endpoints
↥List of similar endpoints to
Xanthelasma of eyelid
based on the number of shared cases.
Similar with more cases:
- Other disorders of eyelid
- Disorders of eyelid, lacrimal system and orbit
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2377 | 1690 | 683 |
| Only index persons | 2263 | 1624 | 639 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.02 |
| Only index persons | 0.05 | 0.06 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 53.93 | 54.29 | 52.96 |
| Only index persons | 53.67 | 54.08 | 52.62 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 277 | 190 | 87 |
| Unadjusted period prevalence (%) | 0.06 | 0.07 | 0.04 |
| Median age at first event (years) | 54.72 | 54.10 | 56.06 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H7_XANTHELASMA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_XANTHELASMA | 1.022 [0.88, 1.19] | 0.785 |
| Birth year | 0.991 [0.98, 1.0] | 0.051 |
During the follow-up period (1.1.1998 — 31.12.2019), 206 out of 1522 females with H7_XANTHELASMA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_XANTHELASMA | 1.057 [0.87, 1.28] | 0.572 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 120 out of 633 males with H7_XANTHELASMA died.
Mortality risk
Mortality risk for people of age
years, who have H7_XANTHELASMA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.096% | 0.197% |
| 5 | 0.591% | 1.24% |
| 10 | 1.353% | 3.169% |
| 15 | 2.571% | 6.058% |
| 20 | 4.416% | 9.757% |
Relationships between endpoints
↥Index endpoint: H7_XANTHELASMA – Xanthelasma of eyelid
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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