eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]
Other retinal disorders in diseases classified elsewhere
DOID EFO Endpoint Browser PheWeb
H7_RETINODISINOTH
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
65 |
4. Check minimum number of eventsNone |
65 |
5. Include endpointsNone |
65 |
6. Filter based on genotype QC (FinnGen only) |
62 |
Control definitions (FinnGen only)
Control exclude
H7_CHOROIDRETINA
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Other retinal disorders in diseases classified elsewhere
based on the number of shared cases.
Similar with more cases:
- Other retinal disorders
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 574 | 264 | 305 |
| Only index persons | 475 | 225 | 250 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 73.40 | 75.61 | 71.43 |
| Only index persons | 71.89 | 74.19 | 69.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 62 | 16 | 46 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | 70.24 | 68.00 | 71.02 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H7_RETINODISINOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINODISINOTH | 2.022 [1.43, 2.87] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.309 |
During the follow-up period (1.1.1998 — 31.12.2019), 112 out of 224 females with H7_RETINODISINOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINODISINOTH | 3.116 [2.09, 4.64] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.013 |
During the follow-up period (1.1.1998 — 31.12.2019), 158 out of 276 males with H7_RETINODISINOTH died.
Mortality risk
Mortality risk for people of age
years, who have H7_RETINODISINOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.201% | 0.653% |
| 5 | 1.355% | 3.505% |
| 10 | 3.207% | 8.552% |
| 15 | 5.726% | 16.384% |
| 20 | 10.189% | 26.337% |
Relationships between endpoints
↥Index endpoint: H7_RETINODISINOTH – Other retinal disorders in diseases classified elsewhere
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data