No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
5622 |
4. Check minimum number of eventsNone |
5622 |
5. Include endpointsNone |
5622 |
6. Filter based on genotype QC (FinnGen only) |
5435 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Retinal breaks without detachment based on the number of shared cases.
Similar with more cases:
- Retinal detachments and breaks
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 37057 | 20151 | 16809 |
Only index persons | 36278 | 19857 | 16421 |
Unadjusted period prevalence (%) | |||
Whole population | 0.53 | 0.58 | 0.47 |
Only index persons | 0.68 | 0.73 | 0.63 |
Median age at first event (years) | |||
Whole population | 60.88 | 60.16 | 61.81 |
Only index persons | 60.82 | 60.09 | 61.71 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 5435 | 3046 | 2389 |
Unadjusted period prevalence (%) | 1.20 | 1.20 | 1.20 |
Median age at first event (years) | 61.17 | 59.50 | 63.29 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H7_RETINALBREAK and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
H7_RETINALBREAK | 0.725 [0.65, 0.81] | < 0.001 |
Birth year | 0.996 [0.99, 1.0] | 0.329 |
During the follow-up period (1.1.1998 — 31.12.2019), 1190 out of 17611 females with H7_RETINALBREAK died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
H7_RETINALBREAK | 0.638 [0.57, 0.71] | < 0.001 |
Birth year | 0.988 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 1476 out of 14412 males with H7_RETINALBREAK died.
Mortality risk
Mortality risk for people of age
years, who have H7_RETINALBREAK.N-year risk | Females | Males |
---|---|---|
1 | 0.062% | 0.134% |
5 | 0.415% | 0.759% |
10 | 1.058% | 1.968% |
15 | 2.039% | 3.615% |
20 | 3.557% | 6.424% |
Relationships between endpoints
↥Index endpoint: H7_RETINALBREAK – Retinal breaks without detachment
GWS hits: 1