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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Other and unspecified postprocedural disorders of eye and adnexa

H7_POSTOPEYENAS

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

53

4. Check minimum number of events

None

53

5. Include endpoints

None

53

6. Filter based on genotype QC (FinnGen only)

48

Control definitions (FinnGen only)

Control exclude H7_EYEPOSTOP

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 541 282 257
Only index persons 456 238 218
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 71.21 72.30 70.00
Only index persons 69.97 70.56 69.33

-FinnGen-

Key figures

All Female Male
Number of individuals 48 28 20
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 66.61 65.17 68.61

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Association

Association between endpoint H7_POSTOPEYENAS and mortality.

Females

Parameter HR [95% CI] p-value
H7_POSTOPEYENAS 1.186 [0.87, 1.61] 0.277
Birth year 0.998 [0.99, 1.01] 0.592

During the follow-up period (1.1.1998 — 31.12.2019), 77 out of 221 females with H7_POSTOPEYENAS died.

Males

Parameter HR [95% CI] p-value
H7_POSTOPEYENAS 1.221 [0.89, 1.68] 0.222
Birth year 0.987 [0.98, 1.0] 0.009

During the follow-up period (1.1.1998 — 31.12.2019), 87 out of 207 males with H7_POSTOPEYENAS died.

Mortality risk

Mortality risk for people of age

years, who have H7_POSTOPEYENAS.

N-year risk Females Males
1 0.158% 0.267%
5 0.729% 1.541%
10 1.938% 3.612%
15 3.787% 6.642%
20 6.666% 11.455%

Relationships between endpoints

Index endpoint: H7_POSTOPEYENAS – Other and unspecified postprocedural disorders of eye and adnexa

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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