No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2841 |
4. Check minimum number of eventsNone |
2841 |
5. Include endpointsNone |
2841 |
6. Filter based on genotype QC (FinnGen only) |
2700 |
Control definitions (FinnGen only)
Control exclude
H7_EYEOTH
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H57
Name in latin
Dolor oculi
Similar endpoints
↥List of similar endpoints to
Ocular pain
based on the number of shared cases.
Similar with more cases:
- Other disorders of eye and adnexa
- Diseases of the eye and adnexa
- Pain (limb, back, neck, head abdominally)
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 20871 | 12553 | 8143 |
| Only index persons | 19651 | 12064 | 7587 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.31 | 0.36 | 0.23 |
| Only index persons | 0.38 | 0.44 | 0.29 |
| Median age at first event (years) | |||
| Whole population | 44.26 | 46.77 | 40.58 |
| Only index persons | 45.21 | 47.44 | 41.68 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2700 | 1953 | 747 |
| Unadjusted period prevalence (%) | 0.66 | 0.77 | 0.38 |
| Median age at first event (years) | 51.95 | 50.34 | 56.15 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H7_OCUPAIN and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_OCUPAIN | 0.915 [0.8, 1.05] | 0.212 |
| Birth year | 0.997 [0.99, 1.01] | 0.54 |
During the follow-up period (1.1.1998 — 31.12.2019), 758 out of 10239 females with H7_OCUPAIN died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_OCUPAIN | 1.1 [0.94, 1.29] | 0.241 |
| Birth year | 0.988 [0.98, 1.0] | 0.01 |
During the follow-up period (1.1.1998 — 31.12.2019), 571 out of 6602 males with H7_OCUPAIN died.
Mortality risk
Mortality risk for people of age
years, who have H7_OCUPAIN.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.098% | 0.206% |
| 5 | 0.573% | 1.275% |
| 10 | 1.386% | 3.209% |
| 15 | 2.831% | 6.125% |
| 20 | 5.097% | 10.639% |
Relationships between endpoints
↥Index endpoint: H7_OCUPAIN – Ocular pain
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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