No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
518 |
4. Check minimum number of eventsNone |
518 |
5. Include endpointsNone |
518 |
6. Filter based on genotype QC (FinnGen only) |
497 |
Control definitions (FinnGen only)
Control exclude
H7_LIDLACRIMALORBIT
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H04
Name in latin
Inflammatio viarum lacrimalium chronica
Similar endpoints
↥List of similar endpoints to
Inflammation of lacrimal passages (chronic)
based on the number of shared cases.
Similar with more cases:
- Disorders of lacrimal system
- Disorders of eyelid, lacrimal system and orbit
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7052 | 5227 | 1789 |
| Only index persons | 5097 | 3749 | 1348 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.15 | 0.05 |
| Only index persons | 0.11 | 0.14 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 63.41 | 65.52 | 57.34 |
| Only index persons | 59.43 | 62.29 | 51.49 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 497 | 346 | 151 |
| Unadjusted period prevalence (%) | 0.12 | 0.14 | 0.08 |
| Median age at first event (years) | 59.54 | 59.63 | 59.32 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H7_LACRIMINFLAMCHRON and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_LACRIMINFLAMCHRON | 0.99 [0.89, 1.11] | 0.858 |
| Birth year | 0.995 [0.99, 1.0] | 0.231 |
During the follow-up period (1.1.1998 — 31.12.2019), 939 out of 2779 females with H7_LACRIMINFLAMCHRON died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_LACRIMINFLAMCHRON | 0.993 [0.84, 1.18] | 0.931 |
| Birth year | 0.991 [0.98, 1.0] | 0.127 |
During the follow-up period (1.1.1998 — 31.12.2019), 290 out of 989 males with H7_LACRIMINFLAMCHRON died.
Mortality risk
Mortality risk for people of age
years, who have H7_LACRIMINFLAMCHRON.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.102% | 0.225% |
| 5 | 0.573% | 1.344% |
| 10 | 1.423% | 3.252% |
| 15 | 2.833% | 6.231% |
| 20 | 5.208% | 10.524% |
Relationships between endpoints
↥Index endpoint: H7_LACRIMINFLAMCHRON – Inflammation of lacrimal passages (chronic)
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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