No definition available.
Keratitis and keratoconjunctivitis in other diseases classified elsewhere
DOID EFO Endpoint Browser PheWeb
H7_KERATITISINOTH
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1215 |
4. Check minimum number of eventsNone |
1215 |
5. Include endpointsNone |
1215 |
6. Filter based on genotype QC (FinnGen only) |
1173 |
Control definitions (FinnGen only)
Control exclude
H7_SCLERACORNEA
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Keratitis and keratoconjunctivitis in other diseases classified elsewhere
based on the number of shared cases.
Similar with more cases:
- Keratitis
- Disorders of sclera, cornea, iris and ciliary body
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9965 | 6270 | 3655 |
| Only index persons | 9295 | 5917 | 3378 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.15 | 0.18 | 0.10 |
| Only index persons | 0.19 | 0.22 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 57.25 | 57.87 | 56.25 |
| Only index persons | 56.48 | 57.07 | 55.45 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1173 | 775 | 398 |
| Unadjusted period prevalence (%) | 0.27 | 0.30 | 0.20 |
| Median age at first event (years) | 57.16 | 54.40 | 62.53 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H7_KERATITISINOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_KERATITISINOTH | 1.172 [1.06, 1.3] | 0.003 |
| Birth year | 0.997 [0.99, 1.01] | 0.498 |
During the follow-up period (1.1.1998 — 31.12.2019), 1256 out of 5773 females with H7_KERATITISINOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_KERATITISINOTH | 1.287 [1.12, 1.47] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 808 out of 3332 males with H7_KERATITISINOTH died.
Mortality risk
Mortality risk for people of age
years, who have H7_KERATITISINOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.122% | 0.217% |
| 5 | 0.79% | 1.381% |
| 10 | 1.877% | 3.322% |
| 15 | 3.525% | 6.138% |
| 20 | 6.137% | 10.284% |
Relationships between endpoints
↥Index endpoint: H7_KERATITISINOTH – Keratitis and keratoconjunctivitis in other diseases classified elsewhere
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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