eyelid disease: A disease involving the eyelid.
Disorders of eyelid in diseases classified elsewhere
DOID EFO Endpoint Browser PheWeb
H7_EYELIDINOTH
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1121 |
4. Check minimum number of eventsNone |
1121 |
5. Include endpointsNone |
1121 |
6. Filter based on genotype QC (FinnGen only) |
1082 |
Control definitions (FinnGen only)
Control exclude
H7_LIDLACRIMALORBIT
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Disorders of eyelid in diseases classified elsewhere
based on the number of shared cases.
Similar with more cases:
- Other disorders of eyelid
- Disorders of eyelid, lacrimal system and orbit
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9999 | 6105 | 3853 |
| Only index persons | 9236 | 5722 | 3514 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.15 | 0.17 | 0.11 |
| Only index persons | 0.18 | 0.21 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 50.95 | 52.09 | 48.97 |
| Only index persons | 49.55 | 51.01 | 47.18 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1082 | 717 | 365 |
| Unadjusted period prevalence (%) | 0.25 | 0.28 | 0.18 |
| Median age at first event (years) | 53.13 | 50.61 | 58.08 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H7_EYELIDINOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_EYELIDINOTH | 1.064 [0.96, 1.18] | 0.229 |
| Birth year | 0.992 [0.98, 1.0] | 0.059 |
During the follow-up period (1.1.1998 — 31.12.2019), 1091 out of 5713 females with H7_EYELIDINOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_EYELIDINOTH | 1.126 [1.0, 1.27] | 0.055 |
| Birth year | 0.987 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 819 out of 3615 males with H7_EYELIDINOTH died.
Mortality risk
Mortality risk for people of age
years, who have H7_EYELIDINOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.085% | 0.236% |
| 5 | 0.602% | 1.414% |
| 10 | 1.425% | 3.493% |
| 15 | 2.699% | 6.594% |
| 20 | 4.826% | 11.058% |
Relationships between endpoints
↥Index endpoint: H7_EYELIDINOTH – Disorders of eyelid in diseases classified elsewhere
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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