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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Other degenerative disorders of globe

H7_DEGENGLOBE

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H44.3
  • Hospital discharge: ICD-9 3602X
  • Cause of death: ICD-10 H44.3
  • Cause of death: ICD-9 3602X

2 out of 7 registries used, show all original rules.

22

4. Check minimum number of events

None

22

5. Include endpoints

None

22

6. Filter based on genotype QC (FinnGen only)

20

Control definitions (FinnGen only)

Control exclude H7_VITREOUS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H44
Name in latin Aliae morbositates degenerativae bulbi oculi

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 147 97 50
Only index persons 136 91 45
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population - 65.61 57.00
Only index persons 60.58 65.09 51.46

-FinnGen-

Key figures

All Female Male
Number of individuals 20 12 8
Unadjusted period prevalence (%) 0.00 0.00 0.00
Median age at first event (years) 53.73 60.30 43.88

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Association

Association between endpoint H7_DEGENGLOBE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H7_DEGENGLOBE.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: H7_DEGENGLOBE – Other degenerative disorders of globe

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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