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Dacryoadenitis

DOID EFO Endpoint Browser PheWeb

H7_DACRYOADENITIS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H04.0
  • Hospital discharge: ICD-9 — 3750
  • Hospital discharge: ICD-8 — 3680[0-1]
  • Cause of death: ICD-10 — H04.0
  • Cause of death: ICD-9 — 3750
  • Cause of death: ICD-8 — 3680[0-1]

2 out of 7 registries used, show all original rules.

248

4. Check minimum number of events

None

248

5. Include endpoints

None

248

6. Filter based on genotype QC (FinnGen only)

241

Control definitions (FinnGen only)

Control exclude H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H04
Name in latin Dacryoadenitis

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2212 1511 693
Only index persons 1950 1344 606
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.02
Only index persons 0.04 0.05 0.02
Median age at first event (years)
Whole population 53.96 56.86 47.52
Only index persons 51.95 55.26 44.61

-FinnGen-

Key figures

All Female Male
Number of individuals 241 166 75
Unadjusted period prevalence (%) 0.06 0.07 0.04
Median age at first event (years) 52.75 51.31 55.94

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

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Association

Association between endpoint H7_DACRYOADENITIS and mortality.

Females

Parameter HR [95% CI] p-value
H7_DACRYOADENITIS 1.049 [0.86, 1.27] 0.633
Birth year 0.995 [0.99, 1.0] 0.239

During the follow-up period (1.1.1998 — 31.12.2019), 219 out of 1134 females with H7_DACRYOADENITIS died.

Males

Parameter HR [95% CI] p-value
H7_DACRYOADENITIS 1.041 [0.76, 1.42] 0.798
Birth year 0.984 [0.97, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 98 out of 509 males with H7_DACRYOADENITIS died.

Mortality risk

Mortality risk for people of age

years, who have H7_DACRYOADENITIS.

N-year risk Females Males
1 0.087% 0.212%
5 0.568% 1.1%
10 1.448% 2.794%
15 2.876% 5.216%
20 5.457% 8.913%

Relationships between endpoints

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Index endpoint: H7_DACRYOADENITIS – Dacryoadenitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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