No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1594 |
4. Check minimum number of eventsNone |
1594 |
5. Include endpointsNone |
1594 |
6. Filter based on genotype QC (FinnGen only) |
1527 |
Control definitions (FinnGen only)
Control exclude
H7_CONJUNCTIVA
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H10
Name in latin
Conjunctivitis allergica acuta
Similar endpoints
↥List of similar endpoints to
Atopic conjunctivitis
based on the number of shared cases.
Similar with more cases:
- Allergic conjunctivitis
- Conjunctivitis
- Disorders of conjunctiva
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 18915 | 10051 | 8786 |
| Only index persons | 16337 | 9105 | 7232 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.27 | 0.29 | 0.25 |
| Only index persons | 0.31 | 0.33 | 0.28 |
| Median age at first event (years) | |||
| Whole population | 21.79 | 30.09 | 12.19 |
| Only index persons | 25.18 | 32.97 | 15.38 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1527 | 1100 | 427 |
| Unadjusted period prevalence (%) | 0.37 | 0.43 | 0.21 |
| Median age at first event (years) | 42.64 | 43.77 | 39.71 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H7_CONJUNCTIVITISATOPIC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONJUNCTIVITISATOPIC | 0.871 [0.76, 0.99] | 0.039 |
| Birth year | 0.999 [0.99, 1.01] | 0.737 |
During the follow-up period (1.1.1998 — 31.12.2019), 495 out of 8736 females with H7_CONJUNCTIVITISATOPIC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONJUNCTIVITISATOPIC | 1.134 [0.97, 1.32] | 0.106 |
| Birth year | 0.994 [0.98, 1.0] | 0.205 |
During the follow-up period (1.1.1998 — 31.12.2019), 326 out of 7543 males with H7_CONJUNCTIVITISATOPIC died.
Mortality risk
Mortality risk for people of age
years, who have H7_CONJUNCTIVITISATOPIC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.104% | 0.293% |
| 5 | 0.654% | 1.533% |
| 10 | 1.512% | 3.981% |
| 15 | 2.959% | 7.591% |
| 20 | 5.068% | 12.889% |
Relationships between endpoints
↥Index endpoint: H7_CONJUNCTIVITISATOPIC – Atopic conjunctivitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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