No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
719 |
4. Check minimum number of eventsNone |
719 |
5. Include endpoints |
747 |
6. Filter based on genotype QC (FinnGen only) |
723 |
Control definitions (FinnGen only)
Control exclude
H7_OCUMUSCLE
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H49-H52
Name in latin
Aliae perturbationes motus binocularis
Similar endpoints
↥List of similar endpoints to
Other disorders of binocular movement
based on the number of shared cases.
Similar with more cases:
- Disorders of ocular muscles, binocular movement, accommodation and refraction
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6549 | 3902 | 2630 |
| Only index persons | 5992 | 3644 | 2348 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.11 | 0.07 |
| Only index persons | 0.12 | 0.13 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 26.83 | 27.34 | 25.99 |
| Only index persons | 28.28 | 28.58 | 27.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 723 | 507 | 216 |
| Unadjusted period prevalence (%) | 0.17 | 0.20 | 0.11 |
| Median age at first event (years) | 37.15 | 34.06 | 44.40 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H7_BINOCUMOVOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_BINOCUMOVOTH | 1.212 [1.03, 1.43] | 0.023 |
| Birth year | 0.996 [0.99, 1.0] | 0.359 |
During the follow-up period (1.1.1998 — 31.12.2019), 225 out of 3488 females with H7_BINOCUMOVOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_BINOCUMOVOTH | 1.596 [1.34, 1.91] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 292 out of 2306 males with H7_BINOCUMOVOTH died.
Mortality risk
Mortality risk for people of age
years, who have H7_BINOCUMOVOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.129% | 0.356% |
| 5 | 0.853% | 1.789% |
| 10 | 1.879% | 4.371% |
| 15 | 3.71% | 8.414% |
| 20 | 6.334% | 13.823% |
Relationships between endpoints
↥Index endpoint: H7_BINOCUMOVOTH – Other disorders of binocular movement
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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