No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
175 |
4. Check minimum number of eventsNone |
175 |
5. Include endpointsNone |
175 |
6. Filter based on genotype QC (FinnGen only) |
167 |
Control definitions (FinnGen only)
Control exclude
H7_OCUMUSCLE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Other and unspecified disorders of binocular movement
based on the number of shared cases.
Similar with more cases:
- Other disorders of binocular movement
- Disorders of ocular muscles, binocular movement, accommodation and refraction
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1678 | 882 | 788 |
| Only index persons | 1432 | 767 | 665 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.03 | 0.02 |
| Only index persons | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 25.62 | 31.82 | 18.49 |
| Only index persons | 29.45 | 33.84 | 24.39 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 167 | 105 | 62 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.03 |
| Median age at first event (years) | 39.82 | 35.93 | 46.42 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H7_BINOCUMOVNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_BINOCUMOVNAS | 1.577 [1.15, 2.17] | 0.005 |
| Birth year | 0.991 [0.98, 1.0] | 0.051 |
During the follow-up period (1.1.1998 — 31.12.2019), 66 out of 658 females with H7_BINOCUMOVNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_BINOCUMOVNAS | 2.058 [1.46, 2.9] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.023 |
During the follow-up period (1.1.1998 — 31.12.2019), 70 out of 582 males with H7_BINOCUMOVNAS died.
Mortality risk
Mortality risk for people of age
years, who have H7_BINOCUMOVNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.113% | 0.431% |
| 5 | 0.795% | 2.599% |
| 10 | 1.949% | 6.692% |
| 15 | 3.791% | 11.912% |
| 20 | 6.634% | 18.919% |
Relationships between endpoints
↥Index endpoint: H7_BINOCUMOVNAS – Other and unspecified disorders of binocular movement
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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