No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
449 |
4. Check minimum number of eventsNone |
449 |
5. Include endpointsNone |
449 |
6. Filter based on genotype QC (FinnGen only) |
438 |
Control definitions (FinnGen only)
Control exclude
H7_OCUMUSCLE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H51
Name in latin
Convergentia insufficiens sive nimia
Similar endpoints
↥List of similar endpoints to
Convergence insufficiency and excess
based on the number of shared cases.
Similar with more cases:
- Other disorders of binocular movement
- Disorders of ocular muscles, binocular movement, accommodation and refraction
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3911 | 2548 | 1357 |
| Only index persons | 3670 | 2423 | 1247 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.07 | 0.04 |
| Only index persons | 0.07 | 0.09 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 19.34 | 21.03 | 16.06 |
| Only index persons | 20.89 | 22.48 | 17.81 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 438 | 333 | 105 |
| Unadjusted period prevalence (%) | 0.11 | 0.13 | 0.05 |
| Median age at first event (years) | 31.95 | 30.36 | 37.01 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H7_CONVERGINSUFF and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONVERGINSUFF | 0.934 [0.75, 1.17] | 0.547 |
| Birth year | 0.992 [0.98, 1.0] | 0.087 |
During the follow-up period (1.1.1998 — 31.12.2019), 83 out of 2408 females with H7_CONVERGINSUFF died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONVERGINSUFF | 1.371 [1.07, 1.76] | 0.012 |
| Birth year | 0.989 [0.98, 1.0] | 0.015 |
During the follow-up period (1.1.1998 — 31.12.2019), 112 out of 1274 males with H7_CONVERGINSUFF died.
Mortality risk
Mortality risk for people of age
years, who have H7_CONVERGINSUFF.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.065% | 0.274% |
| 5 | 0.501% | 1.774% |
| 10 | 1.179% | 4.347% |
| 15 | 2.336% | 8.311% |
| 20 | 4.254% | 13.689% |
Relationships between endpoints
↥Index endpoint: H7_CONVERGINSUFF – Convergence insufficiency and excess
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data