facial neuralgia: Neuralgic syndromes which feature chronic or recurrent facial pain as the primary manifestation of disease. Disorders of the trigeminal and facial nerves are frequently associated with these conditions.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1748 |
4. Check minimum number of eventsNone |
1748 |
5. Include endpointsNone |
1748 |
6. Filter based on genotype QC (FinnGen only) |
1687 |
Control definitions (FinnGen only)
Control exclude
G6_NERPLEX
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G50
Name in latin
Dolor facialis atypicus
Similar endpoints
↥List of similar endpoints to
Atypical facial pain
based on the number of shared cases.
Similar with more cases:
- Nerve, nerve root and plexus disorders
- Neurological diseases
- Neurological diseases
- Pain (limb, back, neck, head abdominally)
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 11362 | 8325 | 2974 |
| Only index persons | 10897 | 8077 | 2820 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.20 | 0.24 | 0.08 |
| Only index persons | 0.25 | 0.30 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 53.80 | 53.86 | 53.78 |
| Only index persons | 53.39 | 53.52 | 53.02 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1687 | 1312 | 375 |
| Unadjusted period prevalence (%) | 0.44 | 0.52 | 0.19 |
| Median age at first event (years) | 53.78 | 52.20 | 59.28 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint G6_ATYFAC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_ATYFAC | 0.927 [0.83, 1.03] | 0.175 |
| Birth year | 0.997 [0.99, 1.01] | 0.527 |
During the follow-up period (1.1.1998 — 31.12.2019), 740 out of 7210 females with G6_ATYFAC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_ATYFAC | 1.044 [0.91, 1.19] | 0.527 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 422 out of 2580 males with G6_ATYFAC died.
Mortality risk
Mortality risk for people of age
years, who have G6_ATYFAC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.089% | 0.176% |
| 5 | 0.585% | 1.204% |
| 10 | 1.481% | 3.141% |
| 15 | 2.898% | 5.834% |
| 20 | 4.971% | 9.832% |
Relationships between endpoints
↥Index endpoint: G6_ATYFAC – Atypical facial pain
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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