No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
97 |
4. Check minimum number of eventsNone |
97 |
5. Include endpointsNone |
97 |
6. Filter based on genotype QC (FinnGen only) |
93 |
Control definitions (FinnGen only)
Control exclude
K11_HERNIA
Extra metadata
First used in FinnGen datafreeze
DF3
Similar endpoints
↥List of similar endpoints to
Femoral hernia, bilateral
based on the number of shared cases.
Similar with more cases:
- Femoral hernia
- Inguinal or femoral hernia, bilateral
- Hernia
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 879 | 487 | 390 |
| Only index persons | 757 | 427 | 330 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.02 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 64.25 | 66.06 | 61.96 |
| Only index persons | 62.17 | 63.86 | 59.99 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 93 | 56 | 37 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | 59.77 | 60.52 | 58.62 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint FEMHER_BILATERAL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| FEMHER_BILATERAL | 1.462 [1.18, 1.81] | < 0.001 |
| Birth year | 1.0 [0.99, 1.01] | 0.999 |
During the follow-up period (1.1.1998 — 31.12.2019), 156 out of 427 females with FEMHER_BILATERAL died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| FEMHER_BILATERAL | 1.338 [1.05, 1.71] | 0.021 |
| Birth year | 0.989 [0.98, 1.0] | 0.022 |
During the follow-up period (1.1.1998 — 31.12.2019), 126 out of 348 males with FEMHER_BILATERAL died.
Mortality risk
Mortality risk for people of age
years, who have FEMHER_BILATERAL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.167% | 0.245% |
| 5 | 0.996% | 1.493% |
| 10 | 2.343% | 3.873% |
| 15 | 4.664% | 7.459% |
| 20 | 7.967% | 12.692% |
Relationships between endpoints
↥Index endpoint: FEMHER_BILATERAL – Femoral hernia, bilateral
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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