No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
899 |
4. Check minimum number of eventsNone |
899 |
5. Include endpointsNone |
899 |
6. Filter based on genotype QC (FinnGen only) |
864 |
Control definitions (FinnGen only)
Control exclude
F5_SCHIZO
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F20-F29
Name in latin
Perturbatio schizotypica
Similar endpoints
↥List of similar endpoints to
Schizotypal disorder
based on the number of shared cases.
Similar with more cases:
- Schizophrenia or delusion
- Schizophrenia or delusion
- Schizophrenia, schizotypal and delusional disorders
- Any mental disorder
- Psychiatric diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7086 | 3051 | 4005 |
| Only index persons | 6600 | 2891 | 3709 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.09 | 0.11 |
| Only index persons | 0.13 | 0.11 | 0.14 |
| Median age at first event (years) | |||
| Whole population | 36.34 | 39.46 | 33.89 |
| Only index persons | 35.74 | 38.80 | 33.36 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 864 | 440 | 424 |
| Unadjusted period prevalence (%) | 0.19 | 0.17 | 0.21 |
| Median age at first event (years) | 34.79 | 35.31 | 34.24 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint F5_SCHIZOTYP and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_SCHIZOTYP | 3.105 [2.62, 3.68] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.117 |
During the follow-up period (1.1.1998 — 31.12.2019), 409 out of 2711 females with F5_SCHIZOTYP died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_SCHIZOTYP | 3.259 [2.88, 3.69] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 565 out of 3557 males with F5_SCHIZOTYP died.
Mortality risk
Mortality risk for people of age
years, who have F5_SCHIZOTYP.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.202% | 0.624% |
| 5 | 1.49% | 3.678% |
| 10 | 3.838% | 9.119% |
| 15 | 7.383% | 16.73% |
| 20 | 12.971% | 26.481% |
Relationships between endpoints
↥Index endpoint: F5_SCHIZOTYP – Schizotypal disorder
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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