No definition available.
Emotional disorders and disorders of social functioning with onset specific to childhood
DOID EFO Endpoint Browser PheWeb
F5_EMOCHILD
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2154 |
4. Check minimum number of eventsNone |
2154 |
5. Include endpointsNone |
2154 |
6. Filter based on genotype QC (FinnGen only) |
2013 |
Control definitions (FinnGen only)
Control exclude
F5_BEHEMOCHILD
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Emotional disorders and disorders of social functioning with onset specific to childhood
based on the number of shared cases.
Similar with more cases:
- Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
- Any mental disorder
- Psychiatric diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 53352 | 27387 | 25927 |
| Only index persons | 46880 | 24830 | 22050 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.75 | 0.78 | 0.72 |
| Only index persons | 0.88 | 0.91 | 0.84 |
| Median age at first event (years) | |||
| Whole population | 12.21 | 13.74 | 10.59 |
| Only index persons | 12.81 | 14.20 | 11.26 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2013 | 1447 | 566 |
| Unadjusted period prevalence (%) | 0.49 | 0.57 | 0.28 |
| Median age at first event (years) | 14.96 | 15.64 | 13.21 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint F5_EMOCHILD and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_EMOCHILD | 2.941 [2.18, 3.97] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.167 |
During the follow-up period (1.1.1998 — 31.12.2019), 248 out of 22080 females with F5_EMOCHILD died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_EMOCHILD | 2.987 [2.26, 3.95] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 286 out of 21256 males with F5_EMOCHILD died.
Mortality risk
Mortality risk for people of age
years, who have F5_EMOCHILD.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.324% | 0.532% |
| 5 | 1.534% | 3.319% |
| 10 | 3.856% | 9.007% |
| 15 | 7.776% | 16.117% |
| 20 | 12.825% | 26.125% |
Relationships between endpoints
↥Index endpoint: F5_EMOCHILD – Emotional disorders and disorders of social functioning with onset specific to childhood
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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