No definition available.
Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
EFO MESH Endpoint Browser PheWeb
F5_BEHEMOCHILD
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
8996 |
6. Filter based on genotype QC (FinnGen only) |
8406 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 196519 | 79805 | 116396 |
| Only index persons | 167819 | 70482 | 97337 |
| Unadjusted period prevalence (%) | |||
| Whole population | 2.85 | 2.29 | 3.25 |
| Only index persons | 3.24 | 2.59 | 3.72 |
| Median age at first event (years) | |||
| Whole population | 11.12 | 13.30 | 9.58 |
| Only index persons | 12.07 | 14.24 | 10.50 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 8406 | 5230 | 3176 |
| Unadjusted period prevalence (%) | 1.88 | 2.05 | 1.60 |
| Median age at first event (years) | 16.07 | 17.07 | 14.42 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint F5_BEHEMOCHILD and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_BEHEMOCHILD | 2.453 [1.74, 3.45] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.498 |
During the follow-up period (1.1.1998 — 31.12.2019), 833 out of 59417 females with F5_BEHEMOCHILD died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_BEHEMOCHILD | 2.805 [2.38, 3.3] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.018 |
During the follow-up period (1.1.1998 — 31.12.2019), 1552 out of 90452 males with F5_BEHEMOCHILD died.
Mortality risk
Mortality risk for people of age
years, who have F5_BEHEMOCHILD.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.254% | 0.473% |
| 5 | 1.587% | 3.408% |
| 10 | 3.706% | 8.411% |
| 15 | 7.211% | 15.558% |
| 20 | 13.156% | 25.812% |
Relationships between endpoints
↥Index endpoint: F5_BEHEMOCHILD – Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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