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Psychotic depression

Endpoint Browser PheWeb

F5_DEPRESSION_PSYCHOTIC

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

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1. Apply sex-specific rule

None

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2. Check conditions

  • not (F5_SCHIZO
  • or F5_SCHIZOAFF
  • or F5_BIPO
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3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 — F32.3, F33.3
  • Hospital discharge: ICD-10 — F32.3, F33.3
  • Hospital discharge: ICD-9 — 2961E
  • Cause of death: ICD-10 — F32.3, F33.3
  • Cause of death: ICD-9 — 2961E

3 out of 7 registries used, show all original rules.

2484

4. Check minimum number of events

None

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5. Include endpoints

None

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6. Filter based on genotype QC (FinnGen only)

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Control definitions (FinnGen only)

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF9

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 2368 1491 877
Unadjusted period prevalence (%) 0.53 0.59 0.44
Median age at first event (years) 47.00 44.27 51.63

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

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Index endpoint: F5_DEPRESSION_PSYCHOTIC – Psychotic depression

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).