Depression or dysthymia

F5_DEPRESSION_DYSTHYMIA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

  • not (F5_SCHIZO
  • or F5_SCHIZOAFF
  • or F5_BIPO
452634

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 F32, F33, F34.1
  • Hospital discharge: ICD-10 F32, F33, F34.1
  • Hospital discharge: ICD-9 2961|2968|3004
  • Cause of death: ICD-10 F32, F33
  • Cause of death: ICD-9 2961|2968|3004

3 out of 7 registries used, show all original rules.

66531

4. Check minimum number of events

None

66531

5. Include endpoints

None

66531

6. Filter based on genotype QC (FinnGen only)

63608

Control definitions (FinnGen only)

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 63608 44683 18925
Unadjusted period prevalence (%) 15.16 17.55 9.50
Median age at first event (years) 44.67 42.70 49.33

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: F5_DEPRESSION_DYSTHYMIA – Depression or dysthymia

GWS hits: 32

This endpoint is excluded (different definition than used in FinnGen).