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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Enterohaemorrhagic Escherichia coli infection

EHEC

dysentery: Acute inflammation of the intestine associated with infectious diarrhea of various etiologies, generally acquired by eating contaminated food containing toxins, biological derived from bacteria or other microorganisms. Dysentery is characterized initially by watery feces then by bloody mucoid stools. It is often associated with abdominal pain; fever; and dehydration.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A04.3
  • Cause of death: ICD-10 A04.3

2 out of 7 registries used, show all original rules.

54

4. Check minimum number of events

None

54

5. Include endpoints

None

54

6. Filter based on genotype QC (FinnGen only)

48

Control definitions (FinnGen only)

Control exclude IBD_BACT_INTEST_INFECTIONS

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 A04
Name in latin Infectio ab Escherichia coli enterohaemorrhagica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 663 320 339
Only index persons 530 259 271
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 18.74 22.76 14.55
Only index persons 26.35 31.04 21.86

-FinnGen-

Key figures

All Female Male
Number of individuals 48 28 20
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 49.54 46.17 54.26

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Association

Association between endpoint EHEC and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have EHEC.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: EHEC – Enterohaemorrhagic Escherichia coli infection

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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