No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
223 |
4. Check minimum number of eventsNone |
223 |
5. Include endpointsNone |
223 |
6. Filter based on genotype QC (FinnGen only) |
202 |
Control definitions (FinnGen only)
Control exclude
E4_ENDOGLAND
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6
Similar endpoints
↥List of similar endpoints to
Precocious central puberty
based on the number of shared cases.
Similar with more cases:
- Hyperfunction of pituitary gland
- Disorders of other endocrine glands
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2852 | 1930 | 912 |
| Only index persons | 2430 | 1642 | 788 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.06 | 0.03 |
| Only index persons | 0.05 | 0.06 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 9.59 | 8.54 | 11.31 |
| Only index persons | 9.31 | 8.52 | 10.97 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 202 | 137 | 65 |
| Unadjusted period prevalence (%) | 0.05 | 0.05 | 0.03 |
| Median age at first event (years) | 10.43 | 8.94 | 13.57 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint E4_PRECOXCENTPUB and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have E4_PRECOXCENTPUB.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: E4_PRECOXCENTPUB – Precocious central puberty
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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