Diabetic neuropathy

DM_NEUROPATHY

diabetic neuropathy: A chronic, pathological complication associated with diabetes mellitus, where nerve damages are incurred due to diabetic microvascular injury involving small blood vessels that supply these nerves, resulting in peripheral and/or autonomic nerve dysfunction.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E1[0-4]4
  • Hospital discharge: ICD-9 2505
  • Hospital discharge: ICD-8 25005
  • Cause of death: ICD-10 E1[0-4]4
  • Cause of death: ICD-9 2505
  • Cause of death: ICD-8 25005

2 out of 7 registries used, show all original rules.

3634

4. Check minimum number of events

None

3634

5. Include endpoints

3634

6. Filter based on genotype QC (FinnGen only)

3503

Control definitions (FinnGen only)

Control exclude DM_COMPLICATIONS
Control conditions DIABETES_FG

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 3503 1244 2259
Unadjusted period prevalence (%) 0.91 0.49 1.13
Median age at first event (years) 59.36 57.19 60.55

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: DM_NEUROPATHY – Diabetic neuropathy

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).