Type 1 diabetes with neuropathy

DM1_NEUROPATHY

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

  • not T2D
398947

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

1258

4. Check minimum number of events

None

1258

5. Include endpoints

1432

6. Filter based on genotype QC (FinnGen only)

1388

Control definitions (FinnGen only)

Control exclude DM_COMPLICATIONS
Control conditions DIABETES_FG

Extra metadata

First used in FinnGen datafreeze DF11

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 1388 597 791
Unadjusted period prevalence (%) 0.33 0.23 0.40
Median age at first event (years) 49.29 45.35 52.27

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: DM1_NEUROPATHY – Type 1 diabetes with neuropathy

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).