This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
D3_SCIDC
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
19 |
4. Check minimum number of eventsNone |
19 |
5. Include endpointsNone |
19 |
6. Filter based on genotype QC (FinnGen only) |
17 |
Control definitions (FinnGen only)
Control exclude
D3_IMMUNEMECHANISM
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D81
Name in latin
Deficientia immunalis mixta gravis cum deficientia sive numero normali cellularum B
Similar endpoints
↥List of similar endpoints to
Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
based on the number of shared cases.
Similar with more cases:
- Combined immunodeficiencies
- Immunodeficiencies
- Certain disorders involving the immune mechanism
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Factors influencing health status and contact with health services
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 194 | 144 | 49 |
| Only index persons | 163 | 130 | 33 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 56.05 | 54.27 | 61.68 |
| Only index persons | 54.39 | 52.61 | 61.43 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 17 | 14 | - |
| Unadjusted period prevalence (%) | 0.00 | 0.01 | - |
| Median age at first event (years) | 50.32 | 47.77 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
Mortality – FinRegistry
↥Association
Association between endpoint D3_SCIDC and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have D3_SCIDC.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: D3_SCIDC – Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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