No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
258 |
4. Check minimum number of eventsNone |
258 |
5. Include endpointsNone |
258 |
6. Filter based on genotype QC (FinnGen only) |
246 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Kela reimbursement Agammaglobulinemia (D80-84) based on the number of shared cases.
Similar with more cases:
- Immunodeficiencies
- Certain disorders involving the immune mechanism
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any reimbursement code in KELA
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 979 | 566 | 411 |
Only index persons | 863 | 510 | 353 |
Unadjusted period prevalence (%) | |||
Whole population | 0.01 | 0.02 | 0.01 |
Only index persons | 0.02 | 0.02 | 0.01 |
Median age at first event (years) | |||
Whole population | 42.67 | 45.86 | 38.29 |
Only index persons | 41.96 | 46.26 | 35.76 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 246 | 158 | 88 |
Unadjusted period prevalence (%) | 0.06 | 0.06 | 0.04 |
Median age at first event (years) | 44.28 | 45.84 | 41.48 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint D3_KELA_IMMUDEF and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
D3_KELA_IMMUDEF | 5.013 [3.21, 7.83] | < 0.001 |
Birth year | 0.998 [0.99, 1.01] | 0.595 |
During the follow-up period (1.1.1998 — 31.12.2019), 53 out of 416 females with D3_KELA_IMMUDEF died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have D3_KELA_IMMUDEF.N-year risk | Females | Males |
---|---|---|
1 | 0.44% | No data |
5 | 3.202% | No data |
10 | 7.618% | No data |
15 | 14.22% | No data |
20 | 23.763% | No data |
Relationships between endpoints
↥Index endpoint: D3_KELA_IMMUDEF – Kela reimbursement Agammaglobulinemia (D80-84)
GWS hits: -