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Malignant neoplasm of breast, HER-positive

Endpoint Browser

C3_BREAST_ERPLUS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only females

265735

2. Check conditions

  • RX_ERPLUS
12994

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C50
  • Cause of death: ICD-9 — 174
  • Cause of death: ICD-8 — 174
  • Cancer registry: Topography ICD-O-3 — C50
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — [23]

2 out of 7 registries used, show all original rules.

12439

4. Check minimum number of events

None

12439

5. Include endpoints

None

12439

6. Filter based on genotype QC (FinnGen only)

12081

Control definitions (FinnGen only)

Control conditions not RX_ERPLUS

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF9

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 12081 12081 -
Unadjusted period prevalence (%) 4.74 4.74 -
Median age at first event (years) 59.90 59.90 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: C3_BREAST_ERPLUS – Malignant neoplasm of breast, HER-positive

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).