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Atopic dermatitis, strict definition with reimbursement

ATOPIC_STRICT_REIMB

atopic eczema: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • KELA reimbursements: KELA codes 134|395|317

1 out of 7 registries used, show all original rules.

2993

4. Check minimum number of events

None

2993

5. Include endpoints

14470

6. Filter based on genotype QC (FinnGen only)

13966

Control definitions (FinnGen only)

Control exclude L12_DERMATITISECZEMA

Extra metadata

First used in FinnGen datafreeze DF3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 13966 9734 4232
Unadjusted period prevalence (%) 3.31 3.82 2.13
Median age at first event (years) 24.16 25.02 22.18

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ATOPIC_STRICT_REIMB – Atopic dermatitis, strict definition with reimbursement

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).