This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Alcoholic myopathy
ALCOMYOP
alcoholic cardiomyopathy: Disease of CARDIAC MUSCLE resulting from chronic excessive alcohol consumption. Myocardial damage can be caused by: (1) a toxic effect of alcohol; (2) malnutrition in alcoholics such as THIAMINE DEFICIENCY; or (3) toxic effect of additives in alcoholic beverages such as COBALT. This disease is usually manifested by DYSPNEA and palpitations with CARDIOMEGALY and congestive heart failure (HEART FAILURE).
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
34 |
4. Check minimum number of eventsNone |
34 |
5. Include endpointsNone |
34 |
6. Filter based on genotype QC (FinnGen only) |
33 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G72
Name in latin
Myopathia alcoholica
Similar endpoints
↥List of similar endpoints to
Alcoholic myopathy
based on the number of shared cases.
Similar with more cases:
- Alcoholic myopathy
- Diseases of the myoneural junction and muscle
- Alcohol use disorder, Swedish definition
- Alcohol related diseases, tilastokeskus definition
- Alcohol related diseases and deaths, all endpoints
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 528 | 123 | 401 |
| Only index persons | 419 | 102 | 317 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.00 | 0.01 |
| Only index persons | 0.01 | 0.00 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 58.43 | 59.95 | 57.98 |
| Only index persons | 58.88 | 60.75 | 58.28 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 33 | 7 | 26 |
| Unadjusted period prevalence (%) | 0.01 | 0.00 | 0.01 |
| Median age at first event (years) | 55.08 | 53.27 | 55.56 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
Mortality – FinRegistry
↥Association
Association between endpoint ALCOMYOP and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ALCOMYOP | 5.951 [3.83, 9.24] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 229 out of 348 males with ALCOMYOP died.
Mortality risk
Mortality risk for people of age
years, who have ALCOMYOP.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 1.083% |
| 5 | No data | 6.329% |
| 10 | No data | 15.561% |
| 15 | No data | 27.789% |
| 20 | No data | 42.051% |
Relationships between endpoints
↥Index endpoint: ALCOMYOP – Alcoholic myopathy
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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